CyberKnife is a cutting-edge robotic radiosurgery system that treats tumors with pinpoint precision—without surgery, pain, or long recovery times.
What Is CyberKnife?
CyberKnife is an advanced robotic radiosurgery system designed to treat cancer anywhere in the body with sub-millimeter precision. Often called the “space scalpel,” this technology uses high-dose radiation beams to destroy tumors without the need for surgical incisions.
Unlike conventional radiotherapy, CyberKnife continuously tracks and adjusts for tumor movement caused by breathing or digestion, ensuring maximum accuracy and protecting healthy tissues.
This non-invasive system can effectively treat a wide range of cancers, including those of the brain, lungs, prostate, pancreas, spine, and head and neck. It is also used for recurrent tumors in areas that have previously received radiation, providing new hope for patients with limited treatment options.
How CyberKnife Works

The CyberKnife System combines advanced imaging, a linear accelerator, and a highly flexible robotic arm to deliver targeted radiation beams from hundreds of different angles.
Key Components:
- Imaging Guidance System: Continuously locates and tracks the tumor during treatment.
- Computer-Controlled Robotic Arm: Adjusts in real time to follow even the slightest tumor movement.
- Robotic Patient Table: Moves precisely in six directions, ensuring perfect alignment throughout the session.
With a robotic accuracy of 0.2 millimeters, CyberKnife delivers radiation exactly where it’s needed—while minimizing damage to surrounding healthy tissues.
Which Cancers Can Be Treated with CyberKnife?
CyberKnife can treat both intracranial (inside the skull) and extracranial (outside the skull) tumors.
Intracranial Conditions:
- Brain metastases
- Gliomas and glioblastomas
- Meningiomas
- Acoustic neuromas
- Pituitary adenomas
- Trigeminal neuralgia
- Arteriovenous malformations (AVMs)
Extracranial Conditions:
- Lung cancer
- Liver cancer
- Pancreatic cancer
- Spinal tumors
- Prostate cancer
- Head and neck cancers
- Adrenal tumors
- Recurrent or metastatic cancers
- CyberKnife can also treat functional disorders such as chronic pain, Parkinson’s disease, and cluster headaches in selected cases.
The CyberKnife Treatment Process
CyberKnife treatment is completely non-surgical and painless. No anesthesia, no incisions, and no hospital stay are required.
- Preparation:
A custom mask or body mold may be used for comfort and to help maintain position. - Imaging:
Before treatment, detailed CT and MRI scans are taken. During therapy, real-time images are compared with these scans to locate the tumor precisely. - Real-Time Tracking:
CyberKnife continuously tracks tumor motion—especially in areas affected by breathing, such as the lungs or liver. Patients can breathe normally during the entire session. - Treatment Delivery:
The robotic arm moves around the patient, delivering hundreds of focused radiation beams directly to the tumor. Each session typically lasts 30 to 90 minutes, and most treatments are completed in 1 to 5 sessions.
After treatment, patients can return to normal daily activities immediately, with no recovery period required.
Benefits of CyberKnife
- Completely non-invasive – No incisions, no pain, no anesthesia.
- Outpatient procedure – No need for hospitalization.
- Exceptional precision – Protects healthy tissues and organs.
- No recovery time – Patients can resume daily life immediately.
- Effective in previously irradiated areas – Can safely re-treat tumors.
- Comfortable and frameless – No rigid head or body frames required.
- Breathing-friendly – No need to hold your breath during treatment.
Compared to other systems like Gamma Knife or TrueBeam, CyberKnife offers the unique ability to track and treat moving tumors with unparalleled flexibility and accuracy.
CyberKnife vs. Gamma Knife
While both are stereotactic radiosurgery systems, they differ in scope and technology:
| Feature | CyberKnife | Gamma Knife |
|---|---|---|
| Target Area | Entire body | Brain only |
| Tumor Tracking | Real-time tracking for moving tumors | Fixed target (no motion tracking) |
| Frames | Frameless and comfortable | Requires rigid head frame |
| Radiation Source | Linear accelerator (X-rays) | Cobalt-60 sources |
| Applications | Brain, spine, lung, prostate, liver, pancreas, and more | Brain lesions only |
CyberKnife’s ability to adapt to movement makes it ideal for treating lung and liver tumors, where breathing can shift tumor position.
CyberKnife Success Rates
Clinical studies have shown excellent outcomes with CyberKnife across various cancer types:
- Brain metastases: 85–95% local control
- Acoustic neuroma and meningioma: 80–90% control rate
- Lung cancer: up to 85% success rate
- Prostate cancer: around 95% success rate with preserved sexual function in most patients
- Spinal tumors: 90% pain relief rate
- Liver and pancreatic tumors: 70–90% tumor control, improved quality of life
Success depends on the tumor’s location, type, and adherence to the full treatment plan.
Why Choose CyberKnife?
CyberKnife provides a safe, precise, and convenient alternative to surgery—especially for patients who are not surgical candidates or wish to avoid invasive procedures.
Its combination of real-time imaging, robotic motion tracking, and targeted radiation delivery makes it one of the most advanced tools in modern cancer care.
💬 Considering CyberKnife Treatment?
If you or a loved one has been diagnosed with a condition that may benefit from CyberKnife, speak to your radiation oncologist or visit a specialized cancer center offering CyberKnife radiosurgery. This technology may offer a faster, more comfortable path to recovery—without the risks of traditional surgery.
🩺 CyberKnife – Frequently Asked Questions (FAQ)
1. What exactly is the CyberKnife System?
CyberKnife is a non-invasive, robotic radiosurgery system that uses highly focused beams of radiation to destroy tumors without surgery. It delivers radiation with sub-millimeter accuracy, minimizing damage to surrounding healthy tissue.
2. Is CyberKnife a type of surgery?
No. Despite the word “knife” in its name, CyberKnife is not surgery. It does not involve incisions, anesthesia, or hospital stays. The treatment is completely non-invasive and painless.
3. What types of cancer can be treated with CyberKnife?
CyberKnife can treat many types of cancer, including:
- Brain and spine tumors
- Lung cancer
- Prostate cancer
- Liver and pancreatic cancer
- Head and neck tumors
- Recurrent or metastatic tumors
It’s also used for certain non-cancerous conditions such as arteriovenous malformations (AVMs) and trigeminal neuralgia.
4. How does CyberKnife differ from traditional radiotherapy?
Traditional radiotherapy treats large areas over many sessions. CyberKnife, however, delivers high doses of focused radiation directly to the tumor in just one to five sessions. Its real-time tracking system adjusts for breathing and body movement, increasing accuracy and reducing side effects.
5. How many sessions will I need?
Most CyberKnife treatments are completed in 1 to 5 sessions, depending on the tumor type and size. Each session typically lasts 30–90 minutes, and patients can go home the same day.
6. Does CyberKnife treatment hurt?
No. The procedure is completely painless. You will lie comfortably on a treatment table while the robotic arm moves around you, delivering radiation beams from multiple angles.
7. Will I need anesthesia or hospitalization?
No anesthesia or hospital stay is required. CyberKnife treatment is performed on an outpatient basis, and most patients return to normal activities immediately after each session.
8. Is CyberKnife safe for previously irradiated areas?
Yes. CyberKnife can safely re-treat tumors in areas that have already received radiation therapy. Its precision allows high-dose treatment without significantly increasing the risk to surrounding tissues.
9. How accurate is CyberKnife?
CyberKnife offers sub-millimeter precision — usually within 0.2 mm. It continuously tracks and adjusts for even the smallest patient or tumor movement, ensuring radiation is always directed exactly where it’s needed.
10. What are the possible side effects of CyberKnife?
Most patients experience minimal or no side effects. Some may have temporary fatigue, mild swelling, or localized tenderness depending on the treated area. Serious complications are extremely rare compared to surgery or conventional radiation therapy.
11. What is the difference between CyberKnife and Gamma Knife?
- Gamma Knife is limited to treating brain lesions and requires a rigid head frame.
- CyberKnife can treat tumors anywhere in the body — including lungs, prostate, spine, and liver — and uses a frameless, comfortable setup.
CyberKnife also tracks tumor motion in real time, something Gamma Knife cannot do.
12. Who is a good candidate for CyberKnife treatment?
CyberKnife is ideal for patients who:
- Have small to medium-sized tumors.
- Cannot undergo surgery due to health risks.
- Have tumors located near vital organs.
- Want a non-invasive alternative to surgery.
A radiation oncologist will review your scans and medical history to determine if CyberKnife is right for you.
13. How soon will I see results after CyberKnife treatment?
Tumor response varies by type. Some tumors shrink within weeks, while others gradually decrease in size over several months. Your doctor will monitor progress through follow-up imaging scans.
14. Can CyberKnife be combined with other cancer treatments?
Yes. CyberKnife is often used alongside chemotherapy, immunotherapy, or surgery, depending on the patient’s treatment plan. Your medical team will determine the most effective approach for your case.
15. What is the success rate of CyberKnife?
Success rates depend on the cancer type:
- Brain and spinal tumors: 85–95% control rate
- Lung cancer: up to 85%
- Prostate cancer: around 95%
- Liver and pancreatic tumors: 70–90% control rate
In general, CyberKnife offers high tumor control with fewer side effects and faster recovery than traditional methods.
16. What happens after the treatment?
After each session, patients can go home immediately. Most return to normal activities the same day. Regular follow-up scans are scheduled to monitor tumor response.
17. Is CyberKnife covered by insurance?
In many countries, CyberKnife treatment is covered by health insurance, especially when prescribed by a radiation oncologist. Coverage varies, so patients should check with their insurance provider in advance.
18. How do I prepare for a CyberKnife session?
No special preparation is needed. You can eat, drink, and take your regular medications unless otherwise advised. Wear comfortable clothing, and plan to relax during the session.
19. Is there an age limit for CyberKnife treatment?
There is no strict age limit. Both younger and elderly patients can safely undergo CyberKnife therapy, as it’s non-invasive and requires no anesthesia.
20. Where can I find a CyberKnife treatment center?
CyberKnife systems are available in major cancer centers worldwide. You can ask your oncologist for a referral or visit official CyberKnife network websites to find certified centers near you.








